Swelling and Biomechanical Studies on Tissue‐Engineered Cartilage
نویسندگان
چکیده
منابع مشابه
Swelling and Biomechanical Properties of Tissue-Engineering Cartilage
Tissue behavior is governed to a large extent by composition and microstructure of the extracellular matrix. In cartilage, various biopolymers (glycosaminoglycans, collagen, hyaluronic acid, etc.) are integrated into a complex network that imparts the tissue with its low-friction characteristics and load-bearing capacity. The structure of collagen (predominantly type II collagen) gives it tensi...
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Mitochondrial swelling induced by valinomycin, calcium chloride and P(i) was studied after potassium permanganate fixation in suspension. Valinomycin induces a rapid K(+) influx, increase of the matrix space and out-folding of the cristae, with good preservation of the matrix material. This swelling is reversible but the cristae do not completely re-form and have a blebbed appearance. On repeat...
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Introduction Cartilage is a complex tissue whose extracellular matrix mainly consists of charged proteoglycan (PG) assemblies imbedded in a fibrous collagen network. PGs attract water and repel each other due to their negative charges generating a high swelling pressure. Collagens are proteins that form the fibrillar meshwork providing cartilage with its tensile strength. Cartilage extracellula...
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Function: The primary function of articular cartilage is mechanical: under load it must deform to distribute the load over a larger area so as to minimize stress in the underlying bone. In addition, articular cartilage must provide a very low friction surface for gliding when the joint is flexed so that articulating joints move freely. Lastly, it must carry out these two functions for a lifetim...
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Hand function requires interaction of muscles, tendons, bones, joints and nerves. The unique construction of the hand provides a wide range of important functions such as manipulation, sense of touch, communication and grip strength (Schieber and Santello 2004). The hand is used in many ways, and in many different situations in our daily lives; so injuries, diseases or deformities of the hand c...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2007
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.21.6.lb3-d